Journal Articles: Recent submissions
Now showing items 4101-4120 of 4120
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Education stakeholders’ contribution to school quality leadership in enhancement of quality education for girls in secondary schools Kenya: A case study of Siaya county
(International Journal of Current Research, 2017-08) -
Antimicrobial activities of crude leaf extract of Solanum Nigrumon Fusarium Oxysporum and Pseudomonas Syringae cultures in Maseno (Kenya)
(Journal of Asian Scientific Research, 2017)Solanum nigrum (black nightshade) is a common short lived perennial plant found in the Kenyan highlands and worldwide in distribution. It is a small highly branched plant that rarely adopt a habit of more than a foot in ... -
Pitting of malaria parasites and spherocyte formation
(Pub Med Central, 2006-07-31)BACKGROUND: A high prevalence of spherocytes was detected in blood smears of children enrolled in a case control study conducted in the malaria holoendemic Lake Victoria basin. It was speculated that the spherocytes ... -
Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial.
(Pub Med Central, 2009-11-17)OBJECTIVE: RTS,S, a candidate vaccine for malaria, is a recombinant protein expressed in yeast containing part of the circumsporozoite protein (CSP) sequence of 3D7 strain of Plasmodium falciparum linked to the hepatitis ... -
Outpatient upper respiratory tract viral infections in children with malaria symptoms in Western Kenya.
(Pub Med Central, 2010-11)A cross-sectional study was performed in children 5 through 10 years of age presenting to outpatient clinics in Nyanza Province, Kenya, in which nasal swab and blood specimens were collected during the high malaria ... -
Malaria prevalence defined by microscopy, antigen detection, DNA amplification and total nucleic acid amplification in a malaria-endemic region during the peak malaria transmission season
(Pub Med Central, 2011-07)OBJECTIVES: To determine the malaria prevalence by microscopy, antigen detection and nucleic acid detection in a defined subpopulation in a Plasmodium falciparum-endemic region during the peak transmission season. ME ... -
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.
(Pub Med Central, 2012-02)Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variation in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ... -
Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria
(Pub Med Central, 2011-08)BACKGROUND: Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young ... -
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality
(Pub Med Central, 2011-12)Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where Plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality
(Pub Med Central, 2012-08)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya.
(Pub Med Central, 2012-06)Background Over the years, reports implicate improper anti-malarial use as a major contributor of morbidity and mortality amongst millions of residents in malaria endemic areas, Kenya included. However, there are limited ... -
Reduced Systemic Bicyclo-Prostaglandin-E2 and Cyclooxygenase-2 Gene Expression are Associated with Inefficient Erythropoiesis and Enhanced Uptake of Monocytic Hemozoin in Children with Severe Malarial Anemia
(Pub Med Central, 2012-08)In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children <48 mos. and manifests as severe malarial anemia [SMA; hemoglobin (Hb)<6.0 g/dL]. Induction of high levels of prostaglandin-E2 ... -
Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating Gamma Interferon Levels
(American Society for Microbiology, 2012)An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) ... -
(−7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
(Bio Med Central, 2013)In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ... -
Effect of Microfinance Services on the Financial Empowerment of Youth in Migori County, Kenya
(Business and Management Review, 2012)The current global youth population is the largest in history. Of the world’s 3 billion people estimated to be under the age of 25, approximately 1.3 billion are between the ages of 15 and 24. This group is faced with ... -
Corporate size, profitability and market value: An econometric panel analysis of listed firms in Kenya
(European Scientific Journal, ESJ, 2015-05-30)In corporate finance, the size of a firm is a primary factor in determining the success of a firm due to economies of scale. While, previous studies have confined their analyses on either a single industry or a few firms, ... -
Associating Biosecurity to Preferences
(Engineers Publication House (EPH), 2017-07)Poultry biosecurity refers to procedures used to prevent the introduction and spread of diseasecarrying organisms in poultry flocks. Literature shows that indigenous chickens are not produced in biosecure conditions raising ... -
Suppressed circulating bicyclo-PGE2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia.
(Biochemical and biophysical research communications, 2013)In holoendemic Plasmodium falciparum transmission regions, malarial anemia is a leading cause of childhood morbidity and mortality. Identifying biomarkers of malaria disease severity is important for identifying at-risk ... -
Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.
(BMC infectious diseases, 2017-04)BACKGROUND: Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of ... -
Towards Clean Information and Communication Technology Campaign in Public Universities in Kenya
(2015-01-04)Information and Communication Technology (ICT) accounts for about 2% of total Greenhouse gas (GHG) emissions. This figure is likely to grow if the use of ICT keeps on growing unmanaged. Rapid technological advances have ...
